Valerie's Notes
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Valerie's Notes     (Manual format 300 pages plus) 
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CLA;  Conjugated Dienoic Derivative of Linoleic Acid;  Tonalin

Conjugated Linoleic Acid is a collective name for a group of modified forms of Linoleic Acid that contain double bonds [conjugation] along the 9th and 11th carbons in the Linoleic Acid molecule - there are eight known isomers (different places on the Linoleic Acid molecule where double bonds may occur), but the cis-10, trans-12 isomer is presently believed to be the most therapeutically active isomer.  Until 1999 it was thought that the cis-9, trans-11 was the most biologically active.  The type known as cis-12, trans-10 is the second most predominant isomer in the CLA group.  Unlike "true" Linoleic Acid, Conjugated Linoleic Acid does not undergo the metabolic transformations associated with Linoleic Acid that lead to the production of Arachidonic Acid.
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Valerie's Notes

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